Yes, you can try this with the following diff:
diff --git a/test/functional/p2p_segwit.py b/test/functional/p2p_segwit.py
index d316c4b602..708e4d7e8f 100755
--- a/test/functional/p2p_segwit.py
+++ b/test/functional/p2p_segwit.py
@@ -1663,6 +1663,7 @@ class SegWitTest(BitcoinTestFramework):
pubkeyhash = hash160(pubkey)
script_pkh = key_to_p2wpkh_script(pubkey)
tx = CTransaction()
+ tx.nLockTime = 0xffffffff
tx.vin.append(CTxIn(COutPoint(temp_utxos[0].sha256, temp_utxos[0].n), b""))
tx.vout.append(CTxOut(temp_utxos[0].nValue, script_pkh))
tx.wit.vtxinwit.append(CTxInWitness())
To add a test, you may have to disable the locktime by setting the sequence number to the right value as well.
I am happy to push a commit that adds a test, if someone writes one.