Disallowing sign-comparison mismatches can help to prevent the introduction of overflow and interpretation bugs.
In this case, ~all~ most existing violations are in the tests, and most simply required annotating the literal as unsigned for comparison.
This was previously prevented by violations in leveldb which were fixed upstream and merged in #17398. You can test that by building this branch against: 22d11187ee3c7abfe9d43c9eb68f102498cc2b9a vs 75fb37ce68289eb7e00e2ccdd2ef7f9271332545